For Healthcare Professionals

Thyroid MWA: from physics to clinical advantage

Microwave ablation (MWA) heats tissue differently from radiofrequency ablation (RFA). Published thyroid studies report substantial nodule reduction and, in selected comparisons, shorter ablation times with MWA.

Physician reviewing a thyroid ultrasound study on a monitor in a clinical setting

Thyroid MWA Mechanism

MWA heats tissue through an electromagnetic field, not an RF current path

An oscillating electromagnetic field causes water molecules in tissue to continuously realign, generating heat around the needle. This mechanism has practical implications for tissue heating, energy delivery, and procedure setup.1,2

Volumetric microwave heating

Microwave energy radiates from the needle tip to heat a targeted tissue volume, rather than relying primarily on conductive heat spread from an electrode.1,2

Less affected by tissue impedance

Compared with RFA, MWA is less affected by rising tissue impedance during heating. It is also less susceptible to heat-sink effects from blood flow.1,2,6

No grounding pad required

MWA does not require a patient-return electrode, eliminating the grounding-pad placement step used in monopolar RFA.2,6

Illustration of a microwave ablation needle positioned in a thyroid nodule generating targeted heat

Clinical Advantages

Thyroid MWA offers distinct clinical advantages

Substantial nodule reduction

Published thyroid studies report substantial nodule volume reduction after MWA, including at 12 months.3,4

Advantage in larger nodules

In an exploratory matched subgroup of nodules ≥3.5 cm (18 per group), MWA achieved a higher 12-month volume reduction rate (VRR) than RFA; overall matched results were comparable.5

Faster ablation

Matched data showed shorter total ablation time and ablation time per unit volume with MWA than RFA.5

Favorable safety profile

Published thyroid MWA studies report low rates of major complications.3,4

Clinical Evidence Snapshot

Published studies show meaningful thyroid MWA outcomes

Two physicians reviewing a thyroid ultrasound study on a monitor in a clinical reading setting
Mean 12-month volume reduction rate

Large benign nodules ≥4 cm

Median ablation time vs RFA

Matched cohort, n=66 per group

Major complications reported in Zhao et al.’s cohort

12-month follow-up; overall complications: 1.95%.

Treatment Positioning

Thyroid MWA addresses key RFA limitations while offering a thyroid-preserving alternative to surgery

Microwave ablation

Uses microwave energy to heat targeted tissue without surgically removing the thyroid gland. No grounding pad is required.2,6

Radiofrequency ablation

Uses electrical current to heat tissue. Rising impedance can limit energy delivery, and monopolar RFA requires a grounding pad.1,2,6

Surgery

Removes part or all of the thyroid, typically under general anesthesia. Thyroid hormone replacement may be needed depending on how much is removed.

System preview
Baird Medical BD-GT microwave ablation generator with a compatible needle in a clinical setting

Baird MWA system

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Indications & Safety

Rx only. The Microwave Ablation System (BD-GT) and the Disposable Microwave Ablation Needle are indicated for coagulation (ablation) of soft tissue. Not intended for cardiac use. The needle is sterile and single use only. Contraindicated in patients with massive bleeding tendency; not recommended for pregnant women; use caution in patients with severe coagulation dysfunction. Potential risks and complications include pain, bleeding or hematoma, swelling, thyroid-function changes, voice changes, and injury to nearby structures. Refer to the Safety Information and the Instructions for Use.

FDA 510(k) K232240 · K232241 · Class II

Clinical Evidence Note

The clinical findings cited here come from published thyroid MWA studies using devices from other manufacturers. Baird Engineering has assessed technical comparability with the Betters platform to support evaluation of the literature's applicability.